Objective:To observe the curative effect of external application of Tongluo Huazheng ointment in adjuvant treatment of hepatitis B cirrhosis of compensatory stage.Methods:Sixty-six cases were randomly divided into two groups,33 cases in each group.Both groups were treated with tenofovir,liver protection and enzyme reduction,and the treatment group were treated with external application of Tongluo Huazheng Ointment.Results:After 6 months of treatment,the indexes of liver function and liver fibrosis in the observation group were lower than those in the control group,while the indexes of coagulation function were shorter than those in the control group(P<0.05).The negative conversion rates of HBeAg and HBV-DNA in the observation group were higher than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the observation group and the control group(P>0.05).Conclusion:External application of Tongluo Huazheng ointment can improve the curative effect in adjuvant treatment of hepatitis B cirrhosis of compensatory stage.
Hepatitis BLiver cirrhosisCompensatory periodExternal application of Tongluo Huazheng Ointment