Objective:To observe the effect of modified Sishen Pills in the treatment of diabetic diarrhea with kidney yang deficiency syndrome.Methods:Eighty-one cases were randomly divided into two groups.Forty-two cases in the treatment group were treated with modified Sishen Pills,while thirty-nine cases in the control group were treated with Clostridium Laurate Bivalent Viable Capsule.Results:The total effective rate of the treatment group was higher than that of the control group(P<0.05).Conclusion:Modified Sishen Pills has good curative effect in the treatment of diabetic diarrhea with kidney yang deficiency syndrome.