Objective:To observe the clinical efficacy of Kidney-tonifying and Blood-activating Decoction combined with cyclophosphamide in the treatment of refractory nephrotic syndrome.Methods:Seven-eight cases were randomly divided into the control group(37 cases)and the observation group(41 cases).The two groups were treated with cyclophosphamide,and the observation group were treated with Bushen Huoxue Decoction in addition.Results:The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the scores of facial edema,aversion to cold,and soreness of the waist and knee in the two groups were lower than those before treatment,and those in the observation group were lower than the control group(P<0.05).After treatment,the levels of BUN and Scr in the two groups decreased,and the decrease in the observation group was more significant than in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Kidney-tonifying and Blood-activating Decoction combined with cyclophosphamide is effective and safe in the treatment of refractory nephrotic syndrome.
Refractory nephrotic syndromeKidney-tonifying and Blood-activating DecoctionCyclophosphamideControl treatment and observation
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维普
