Objective:To observe the clinical effect of Shengji Zhitong Decoction combined with Kangfuxin Liquid on postoperative perianal abscess.Methods:Ninety cases were divided into two groups,with 45 cases in each group.Both groups were treated with Kangfuxin Liquid after operation,and the combined group were treated with Shengji Zhitong Decoction with hip bath in addition.Results:The effective rate of the combined group was higher than that of the control group(P<0.05).After 14 days of treatment,the wound secretions,wound granulation growth and pain scores of the combined group were lower than those of the control group,and the wound healing time was shorter than that of the control group(P<0.05).After 14 days of treatment,the levels of IL-1β and TNF-α in the combined group were lower than those in the control group while EGF was higher than that in the control group(P<0.05).After 14 days of treatment,the levels of CD4+,CD4+/CD8+and CD3+in the combined group were higher than those in the control group(P<0.05).After 14 days of treatment,the maximum anal systolic pressure and anal resting pressure in the combined group were lower than those in the control group(P<0.05).Conclusion:Shengji Zhitong Decoction combined with Kangfuxin Liquid could reduce inflammation and pain,enhance immunity,improve anal function and promote rehabilitation after perianal abscess surgery.