首页|海马益智散辅治阿尔茨海默病临床研究

海马益智散辅治阿尔茨海默病临床研究

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目的:观察海马益智散辅治阿尔茨海默病(AD)脾肾两虚型的疗效.方法:64例按照随机数字表法分为观察组和对照组各32例.两组均用盐酸多奈哌齐片,观察组加用海马益智散,共治疗12周.结果:观察组总有效率高于对照组(P<0.05).治疗后两组MMSE评分、ADL评分均高于治疗前(P<0.05)而ADAS-cog评分低于治疗前(P<0.05),观察组MMSE、ADL评分高于对照组(P<0.05)而ADAS-cog评分低于对照组(P<0.05).观察组治疗后QOL-AD量表评分高于治疗前(P<0.05).结论:海马益智散加减辅治AD可提高临床疗效.
Objective:To observe the curative effect of Haima Yizhi Powder on Alzheimer's disease(AD)with spleen and kidney deficiency.Methods:Sixty-four cases were divided into observation group and control group according to the random number table method,with 32 cases in each group.Both groups were treated with donepezil hydrochloride tablets,and the observation group were treated with Haima Yizhi Powder for 12 weeks.Results:The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the MMSE score and ADL score of the two groups were higher than those before treatment(P<0.05),while the ADAS-cog score was lower than that before treatment(P<0.05).The MMSE and ADL scores of the observation group were higher than those of the control group(P<0.05),while the ADAS-cog score was lower than that of the control group(P<0.05).The QOL-AD Scale score of the observation group after treatment was higher than that before treatment(P<0.05).Conclusion:Modified Haima Yizhi Powder could improve the clinical efficacy in the treatment of AD.

Alzheimer's diseaseHaima Yizhi PowderControl treatment and observation

邵晶、吕书勤

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新疆医科大学第四临床医学院,新疆 乌鲁木齐 830000

新疆医科大学第四临床医学院干部病房,新疆 乌鲁木齐 830000

阿尔茨海默病 海马益智散 对照治疗观察

2024

实用中医药杂志
重庆医科大学中医药学院

实用中医药杂志

影响因子:0.546
ISSN:1004-2814
年,卷(期):2024.40(5)
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