实用中医药杂志2024,Vol.40Issue(5) :881-884.

参麦注射液联合血必净注射液辅治重症肺炎临床研究

耿琪
实用中医药杂志2024,Vol.40Issue(5) :881-884.

参麦注射液联合血必净注射液辅治重症肺炎临床研究

耿琪1
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作者信息

  • 1. 河南省开封市中医院药学部,河南 开封 475002
  • 折叠

摘要

目的:观察参麦注射液联合血必净注射液辅治重症肺炎的效果.方法:80例根据随机数字表法分为两组各40例.两组均给予西医治疗,联合治疗组同时给予参麦注射液、血必净注射液治疗.结果:治疗后联合治疗组IFN-γ、IL-17指标低于基础治疗组(P<0.05),IL-4、TGF-β指标高于基础治疗组(P<0.05).联合治疗组GSH-Px、CD4+指标高于基础治疗组(P<0.05),RAGE、CD8+指标低于基础治疗组(P<0.05).联合治疗组Raw、PIP、WOB指标低于基础治疗组(P<0.05),Cdyn指标高于基础治疗组(P<0.05).联合治疗组Lac、PaCO2指标低于基础治疗组(P<0.05),PaO2、氧合指数指标高于基础治疗组(P<0.05).联合治疗组CPIS、Murray评分低于基础治疗组(P<0.05),总有效率高于基础治疗组(P<0.05).结论:参麦注射液联合血必净注射液辅治重症肺炎可提高疗效.

Abstract

Objective:To observe the effect of Shenmai Injection combined with Xuebijing Injection in the treatment of severe pneumonia.Methods:Eighty cases were divided into two groups according to the random number table method,with 40 cases in each group.Both groups were treated with western medicine,and the combined treatment group were treated with Shenmai Injection and Xuebijing Injection at the same time.Results:After treatment,the indexes of IFN-γ and IL-17 in the combined treatment group were lower than those in the basic treatment group(P<0.05),and the indexes of IL-4 and TGF-β were higher than those in the basic treatment group(P<0.05).The GSH-Px and CD4+indexes in the combined treatment group were higher than those in the basic treatment group(P<0.05),and the RAGE and CD8+indexes were lower than those in the basic treatment group(P<0.05).The indexes of Raw,PIP and WOB in the combined treatment group were lower than those in the basic treatment group(P<0.05),and the Cdyn index was higher than that in the basic treatment group(P<0.05).The indexes of Lac and PaCO2 in the combined treatment group were lower than those in the basic treatment group(P<0.05),and the indexes of PaO2 and oxygenation index were higher than those in the basic treatment group(P<0.05).The CPIS and Murray scores of the combined treatment group were lower than those of the basic treatment group(P<0.05),and the total effective rate was higher than that of the basic treatment group(P<0.05).Conclusion:Shenmai Injection combined with Xuebijing Injection in the treatment of severe pneumonia could improve the curative effect.

关键词

重症肺炎/参麦注射液/血必净注射液

Key words

Severe pneumonia/Shenmai Injection/Xuebijing Injection

引用本文复制引用

出版年

2024
实用中医药杂志
重庆医科大学中医药学院

实用中医药杂志

影响因子:0.546
ISSN:1004-2814
参考文献量18
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