首页|皮内针联合中药熏蒸辅治干燥综合征相关性干眼症临床观察

皮内针联合中药熏蒸辅治干燥综合征相关性干眼症临床观察

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目的:观察皮内针联合中药熏蒸治疗干燥综合征相关性干眼症(SS-DED)的临床疗效。方法:60例用随机数字表法分为对照组和观察组各30例。两组均用常规西药治疗,观察组加用皮内针联合中药熏蒸治疗。结果:总有效率观察组高于对照组(P<0。05)。治疗后观察组中医证候积分、眼表疾病指数量表(OSDI)、免疫球蛋白IgG、红细胞沉降率(ESR)水平均低于对照组(P<0。05),泪液分泌量(SIT)、泪膜破裂时间(BUT)高于对照组(P<0。05)。治疗后两组免疫球蛋白IgM、类风湿因子(RF)水平比较差异无统计学意义(P>0。05)。不良反应发生率观察组低于对照组(P<0。05)。结论:皮内针联合中药熏蒸辅治SS-DED较单纯西医治疗疗效更好,且安全性更高。
Objective:To observe the clinical efficacy of intradermal needle combined with traditional Chinese medicine fumigation in the treatment of Sjogren's syndrome-related dry eye(SS-DED).Methods:Sixty cases were randomly divided into the control group and the observation group,with 30 cases in each group.Both groups were treated with conventional western medicine,and the observation group was treated with intradermal needle combined with traditional Chinese medicine fumigation.Results:The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the scores of TCM syndromes,ocular surface disease index(OSDI),immunoglobulin IgG and erythrocyte sedimentation rate(ESR)in the observation group were lower than those in the control group(P<0.05),and the tear secretion(SIT)and tear film rupture time(BUT)were higher than those in the control group(P<0.05).There was no significant difference in the levels of immunoglobulin IgM and rheumatoid factor(RF)between the two groups after treatment(P>0.05).The incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion:Intradermal needle combined with traditional Chinese medicine fumigation is more effective and safer than simple western medicine in the treatment of SS-DED.

Sjogren's syndrome associated dry eyeIntradermal needleChinese medicine fumigationControl treatment and observation

李雄、荣晓凤

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重庆医科大学,重庆 400016

重庆医科大学附属第一医院中西医结合科,重庆 400042

干燥综合征相关性干眼症 皮内针 中药熏蒸 对照治疗观察

2024

实用中医药杂志
重庆医科大学中医药学院

实用中医药杂志

影响因子:0.546
ISSN:1004-2814
年,卷(期):2024.40(5)
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