Objective:To observe the effect of Erxian Decoction on osteoporosis.Methods:Eighty-eight cases were randomly divided into the control group and the observation group,with 44 cases in each group.Both groups were treated with conventional western medicine,and the observation group were treated with Erxian Decoction in addition.Results:The total effective rate of the observation group was higher than that of the control group(P<0.05).The TCM syndrome score of the observation group was lower than that of the control group(P<0.05).After treatment,type I procollagen amino terminal propeptide(PINP)and type I collagen carboxy terminal peptide β special sequence(β-CTX)in the observation group were lower than those in the control group,while bone morphogenetic protein 6(BMP6)was higher than that in the control group(P<0.05).After treatment,the inflammatory factors interleukin-1(IL-1),nuclear factor(NF-κB)and tumor necrosis factor-α(TNF-α)in the observation group were lower than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Erxian Decoction is effective and safe in the treatment of osteoporosis.
OsteoporosisErxian DecoctionControl treatment and observation
万方数据
维普
