Objective:To observe the efficacy of modified Zhenwu Decoction as an adjuvant therapy in the treatment of chronic heart failure(CHF)with yang deficiency and water accumulation syndrome.Methods:A total of 110 patients were randomly divided into a treatment group and a control group,with 55 patients in each group.Both groups received conventional Western medical treatment,and the treatment group additionally received modified Zhenwu Decoction.Results:The total effective rate was higher in the treatment group than the control group(P<0.05).After treatment,the traditional Chinese medicine(TCM)syndrome scores were lower in the treatment group than in the control group(P<0.05).The improvement in cardiac function was superior in the treatment group than the control group(P<0.05).Vascular endothelial function markers such as NO and ET-1,inflammatory factors including CTGF and TGF-β1,and cardiac function indicators like BNP were all improved in both groups post-treatment compared to pre-treatment(P<0.05),with the treatment group showing better improvements than the control group(P<0.05).The exercise tolerance and quality of life(QOL)scores were better in the treatment group than the control group(P<0.05).Conclusion:Modified Zhenwu Decoction has good efficacy in adjuvant treatment of chronic heart failure with yang deficiency and water accumulation syndrome.
Chronic heart failureYang deficiency and water accumulation syndromeModified Zhenwu Decoction
万方数据
维普
