Objective:To observe the efficacy of Sanhuang Ointment combined with levocetirizine hydrochloride in the treatment of atopic dermatitis(AD).Methods:A total of 100 patients were randomly divided into a control group and an observation group,with 50 patients in each group.Both groups received oral levocetirizine hydrochloride.The control group additionally applied hydrocortisone butyrate topically,while the observation group received Sanhuang Ointment for external application.Results:The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,both groups showed a decrease in lesion area,severity,pruritus and sleep scores,as well as overall scores and the levels of IgE,IL-2,TNF-α and IL-17.The observation group exhibited lower levels compared to the control group(P<0.05).Furthermore,there was an increase in sebum content and stratum corneum hydration in both groups,with the observation group showing higher levels than the control group(P<0.05).Conclusion:The combination of Sanhuang Ointment and levocetirizine hydrochloride is effective in the treatment of AD.
万方数据
维普
