摘要
目的:观察乌梅丸辨证加减联合温针灸治疗溃疡性结肠炎(UC)的效果.方法:120例按照随机数字表法分为两组各60例.对照组用西医常规治疗,试验组用乌梅丸辨证加减联合温针灸治疗.结果:试验组总有效率高于对照组(P＜0.05),两组治疗后中医证候积分均下降且试验组低于对照组(P＜0.05),两组治疗后结肠镜评分均降低且试验组低于对照组(P＜0.05),两组治疗后疾病活动指数(DAI)评分均降低且试验组低于对照组(P＜0.05),两组治疗后丙二醛(MDA)、超氧化物歧化酶(SOD)水平均升高且试验组高于对照组(P＜0.05),两组不良反应发生率比较差异无统计学意义(P＞0.05).结论:乌梅丸辨证加减联合温针灸治疗UC疗效较好,且不良反应少.
Abstract
Objective:To observe the effect of Mume Pills combined with warm acupuncture in the treatment of ulcerative colitis(UC).Methods:A total of 120 cases were divided into two groups according to the random number table method,with 60 cases in each group.The control group were treated with conventional western medicine while the experimental group were treated with Mume Pills combined with warm acupuncture.Results:The total effective rate of the experimental group was higher than that of the control group(P<0.05).The TCM syndrome scores of the two groups decreased after treatment and the experimental group was lower than the control group(P<0.05).The colonoscopy scores of the two groups decreased after treatment and those in the experimental group was lower than the control group(P<0.05).The disease activity index(DAI)scores of the two groups decreased after treatment and those in the experimental group was lower than the control group(P<0.05).The levels of malondialdehyde(MDA)and superoxide dismutase(SOD)in the two groups increased after treatment and those in the experimental group was higher than the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Mume Pills combined with warm acupuncture has a good curative effect on UC with less adverse reactions.
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