半仿生法提取白附子的工艺研究
Optimization of Semi-bionic Extraction of Rhizoma Typhonii
曹志友 1王新城 1欧阳瑾 1雷钧涛2
作者信息
- 1. 吉林医药学院直属医院,吉林,吉林112013
- 2. 吉林医药学院·药学院,吉林,吉林132013
- 折叠
摘要
目的 优化白附子最佳提取工艺.方法 以β-谷甾醇得率为指标,在提取次数、提取工艺、浸渍剂浓度等条件相同时,考虑乙醇溶液pH 值、提取时间、提取温度,选用L16(45)正交进行实验,确定最佳提取工艺.结果 最佳提取工艺为第1煎提取液pH为7,第2煎提取液pH为9,提取温度85℃,提取时间6 h.结论 半仿生提取法优选白附子最佳提取工艺,方法简便,可行.
Abstract
Objective To optimize the semi-bionic extraction of Rhizoma Typhonii.Methods Under the unchanged conditions including extracting frequency,extracting course and concentration of solvent,with the yield rate of isoflavonoids of Rhizoma Typhonii as index as index,L16(45) orthogonal design was used to investigate the effects of pH,extraction temperature,and extraction time.Results The first extraction pH was 7.The second extraction pH was 9.The extraction temperature was 85 ℃.The extraction time was 6 hours.Conclusion Optimization of semibionic extraction methods of Rhizoma Typhonii by orthogonal design is available.
关键词
白附子/半仿生提取法/β-谷甾醇/正交设计Key words
White aconite/SBE law/β-sitosterol/Orthogonal design引用本文复制引用
基金项目
吉林省教育厅重点项目(吉教科合字[2007]第242号)
出版年
2009
国家科技期刊平台
NSTL
维普
万方数据