首页|雪胆胃肠丸对胃溃疡的作用实验研究

雪胆胃肠丸对胃溃疡的作用实验研究

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目的 考察雪胆胃肠丸对实验性胃溃疡的作用.方法 采用小鼠无水乙醇致胃溃疡和大鼠乙酸致胃溃疡模型,考察雪胆胃肠丸对抗实验性胃溃疡的作用.采用小鼠醋酸扭体实验和小鼠耳廓肿胀实验考察其镇痛和抗炎作用.结果 雪胆胃肠丸均能使小鼠无水乙醇所致胃溃疡的溃疡面积明显减小,能降低大鼠溃疡指数,可降低醋酸致小鼠扭体反应的次数,抑制巴豆油致小鼠耳廓肿胀.结论 雪胆胃肠丸对实验性胃溃疡有明显的保护作用.
Experimental Research on Effects of Xue Dan Wei Chang Pill on Gastric Ulcer
Objective To study the effects of Xue Dan Wei Chang pill on experimental gastric ulcer.Methods Acetic acid model in rats and absolute ethanol gavage model in mice were used to study the anti-gastric ulcer effect.The mouse stretching model caused by acetic acid and the auricle swelling caused by croton oil in mice were adopted to study the analgesia and antiinflammatory effects of Xue Dan Wei Chang pill.Results Xue Dan Wei Chang pill could reduce the areas of gastric ulcer caused by absolute alcohol in mice and acetic acid in rats,inhibit the auricle swelling caused by croton oil in mice and the number of stretching induced by acetic acid in mice.Conclusion Xue Dan Wei Chang pill has protective effects on the experimental gastric ulcer.

Xue Dan Wei Chang pillGastric ulcerAnalgesiaAntiinflammatory

刘艳丽、李笑然、范金胤、许琼明、杨世林

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苏州大学医学部药学院,江苏,苏州,215123

雪胆胃肠丸 胃溃疡 镇痛 抗炎

国家科技支撑计划重点项目子课题贵州中药现代化项目

2006BA108B03-052008GZ00371

2010

时珍国医国药
时珍国医国药杂志社

时珍国医国药

CSCD北大核心
影响因子：0.887
ISSN：1008-0805
年,卷(期)：2010.21(2)
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