Preparation of YangyinQingfeiYin and its protective effect on radio pneumonia in rats
Objective To introduce the preparation method and to explore the effects and the underlying mechanism of Yangyin-QingfeiYin,a Chinese fomula,on preventing and treating radio pneumonia in rats.Methods To establish the model of rat radia-tion lung injury and Interventions through gavage,then followed by pathological examination of lung tissue and the expression of Cleavage-Caspase3、Bax and Bel-2 Protein were detected by Western blot.Results The YangyinQingfeiYin was preparated suc-cessfully and it could significantly reduce inflammation of lung tissue and markedly suppress Bax,cleavage-caspase3 Protein and increase Bcl-2 Protein in rats with radiation-induced lung injury.Conclusion YangyinQingfeiYin could reduce inflammation of radiation lung injury in rats through inhibiting apoptosis.
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