The Box-Behnken response surface method to optimize the preparation technology of Succus bambusae pinella preparata
Objective In order to optimize the preparation technology of Succus bambusae pinella preparata,and so as to provide a reference for the standardized research on the prescription-based processing of Succus bambusae pinella preparata.Method-s Using the Box-Behnken response surface method design and analysis,taking the comprehensive scores of extractable,hypo-xanthine,uridine,adenine and guanosine as the evaluation index,the three factors of excipient dosage,drying temperature and processing time of Succus bambusae pinella preparata were investigated,and the preparation technology of Succus bambusae pinel-la preparata was optimized,and the best process was used to verify it.Results The best conditions for the preparation technology of Succus bambusae pinella preparata were 100 g of Pinelliae Rhizoma Praeparatum cum Zingibere et Alumine,the fresh bamboo sap was 15 g,the processing time was 1 h,and the drying temperature was 44℃.Conclusion The preparation technology is sim-ple and feasible,and the quality of Succus bambusae pinella preparata is stable and reliable,which provides a scientific basis for the clinical application of Succus bambusae pinella preparata.
Succus bambusae pinella preparataBox-Behnken response surface methodologyProcessing technologyOverall desirability value
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