Clinical observation and safety evaluation of Chinese medicine Shengfa tincture combined with Plum blossom needle in the treatment of androgenetic alopecia
Objective To investigate the clinical efficacy and safety of Shengfa tincture combined with plum blossom needle in the treatment of androgenetic alopecia.Methods A total of 80 AGA patients were divided into observation group(40 cases,3 cases dropped off)and control group(40 cases,5 cases dropped off)according to the random number table method.The observation group was treated with Shengfa tincture for external use,and the control group was treated with minoxidil liniment for external use.Both groups were treated with plume needle percussion for 24 weeks.Before and after treatment,the objective indicators(hair density and hair diameter)under the hair microscope in the fixed alopecia observation area,clinical symptom scores(scalp greas-iness,itching,desquamation),Hamilton Depression Scale scores and Hamilton Anxiety Scale scores were compared to explore the therapeutic effect of Chinese medicine Shengfa TCD on AGA.The safety of Shengfa tincture in the treatment of AGA was eval-uated by comparing the incidence of adverse reactions between the two groups.Results After 24 weeks of treatment,the total ef-fective rates of the observation group and the control group were 86.49％and 71.43％,respectively,and the effect of the obser-vation group was better than that of the control group(P＜0.05).After treatment,the improvement of hair density in the obser-vation group was higher than that in the control group(P＜0.05),and the clinical symptom score,HAMA score,HAMD score,and adverse reaction rate were lower than those in the control group(P＜0.05).Conclusion Chinese medicine Shengfa tincture combined with plum blossom needle in the treatment of AGA has significant clinical effect and is convenient to use,and no obvious adverse reactions occur.
Androgenic alopeciaChinese medicine Shengfa tincturePlum blossom needle
NETL
NSTL
万方数据
