Current Situation of Molecular Biology Research on Blood Stasis and Toxin Syndrome of Coronary Heart Disease
Blood stasis and toxin syndrome of coronary heart disease(CHD)is the pathogenesis transformation theory based on the transformation process from stable stage of CHD to unstable stage of CHD.It is closely related to the dysfunction of vascular en-dothelial cell,hemorheology,platelet function,coagulation and fibrinolytic system,lipid metabolism disorder,inflammatory re-sponse and intestinal flora disorder.This paper discusses the biological essence of the CHD development theory of"blood stasis accumulates into toxin,and toxin causes catastrophe"from physicochemical index and molecular biology,aiming to provide refer-ence for objectifying blood stasis and toxin syndrome,as well as provide ideas and methods for further developing the diagnostic technique and treatment of CHD blood stasis and toxin syndrome with integration of Traditional Chinese Medicine and Western medicine.
Coronary heart diseaseBlood stasis and toxin syndromeMolecular biologyPathogenesis