Objective To study the chemical constituents of Stelleropsis tianschanica(Pobed),a Thymelaeaceae plant.Methods Using column chromatography to separate and purify the pure methanol extract of Stelleropsis tianschanica(Pobed)and the struc-ture of the compound was rationalized and identified using nuclear magnetic resonance NMR and high-resolution mass spectrome-try.The filter paper method was used to screen the antibacterial activity of monomeric compounds at different concentrations.Re-sults Eight compounds were obtained and identified as(E)-11-methoxy-11-oxoundec-2-enoic acid(1)、Methyl-(E)-9-oxooctadec-10-enoate(2)、3-Hydroxyphthalimide(3)、Dimethyl hexadecanedioate(4)、Octadecane-1,18-dimethyl-ester(5)、9-methoxy-9-oxononanoic acid(6)、n-Hcxadecane acid(7)、Bothrioclinin(8)、Daphnolon(9)、β-sitostcrol(10)、Sesamin(11).Compound 7(128 μg/ml)had some inhibitory activity against Staphylococcus aureus,with a size of 8.65mm of the antibacterial ring,and compound 9(128 μg/ml and 64 µg/ml)had inhibitory activity against Acinetobacter bau-mannii,with antibacterial ring of 12.65 mm and 8.05 mm.Conclusion Compounds 1～9 were obtained from this plant for the first time and the 13 C-NMR data of compounds 1～3 were reported for the first time.Compounds 7 and 9 showed certain antimicrobial activity.
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