首页|生髓健骨胶囊治疗酒精性骨质疏松症的临床疗效观察

生髓健骨胶囊治疗酒精性骨质疏松症的临床疗效观察

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目的 观察对比生髓健骨胶囊与阿仑膦酸钠片在治疗酒精性骨质疏松症的临床疗效差异,阐述中药在酒精性骨质疏松症治疗中的优势。方法 确诊为酒精性骨质疏松症患者90例。使用随机数字表法分为两组,每组各45例患者,治疗组口服生髓健骨胶囊治疗,对照组口服阿伦磷酸钠治疗,并且两组患者同时使用甘草酸二铵肠溶胶囊和钙尔奇D3片。对比观察两组患者治疗前、后视觉模拟评分(VAS)、腰椎骨密度值(BMD)、血清碱性磷酸酶(ALP)以及肝功指标、血压和心电图的变化。结果 治疗后两组腰椎骨密度值、ALP水平与对照组差异较小,但在肝功指标上存在差异。结论 生髓健骨胶囊与阿仑膦酸钠片在治疗酒精性骨质疏松症方面疗效相当,但生髓健骨胶囊对患者肝脏功能负担更小。
Clinical Observation on the Therapeutic Effect of Shengsui Jiangu Capsule on Alcoholic Osteoporosis
Objective To observe and compare the clinical efficacy of Shengsui Jiangu capsule and alendronic acid sodium tablet in the treatment of alcoholic osteoporosis,and elaborate the advantages of traditional Chinese medicine in the treatment of alcohol-ic osteoporosis.Methods 90 patients diagnosed with alcoholic osteoporosis were selected.Using a random number table method,the patients were divided into two groups,with 45 patients in each group.The treatment group received oral treatment with Sheng-sui Jiangu Capsules,while the control group received oral treatment with alenophosphate sodium.Both groups of patients were also treated with diammonium glycyrrhetinic acid enteric coated capsules and calcic D3 tablets.Compare and observe the changes in visual analogue score(VAS),lumbar bone mineral density(BMD),serum alkaline phosphatase(ALP),liver function indica-tors,blood pressure,and electrocardiogram of the two groups of patients before and after treatment.Results After treatment,there was little difference in lumbar bone density and ALP levels between the two groups compared to the control group,but there were differences in liver function indicators.Conclusion Shengsui Jiangu Capsule and alendronic acid Sodium Tablets have the same efficacy in the treatment of alcoholic osteoporosis,but Shengsui Jiangu Capsule has less burden on the liver function of pa-tients.

Shengsui Jiangu CapsuleAlcoholic osteoporosis

任树军、马正印、周宏政、申意伟、谭福柱、李远峰、徐西林

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黑龙江中医药大学附属第一医院,黑龙江哈尔滨 150040

黑龙江中医药大学,黑龙江哈尔滨 150040

黑龙江中医药大学附属第四医院,黑龙江哈尔滨 150018

北京中医药大学深圳医院(龙岗),广东深圳 518172

黑龙江中医药大学附属第三医院,黑龙江哈尔滨 150016

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生髓健骨胶囊 酒精性性骨质疏松症

黑龙江省自然科学基金联合引导项目黑龙江省自然科学基金

LH2020H086H2017055

2024

时珍国医国药
时珍国医国药杂志社

时珍国医国药

北大核心
影响因子:0.887
ISSN:1008-0805
年,卷(期):2024.35(4)
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