首页|基于"阳微阴弦"理论探讨慢性心衰中医证候的生物标志物及中药干预

基于"阳微阴弦"理论探讨慢性心衰中医证候的生物标志物及中药干预

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《金匮要略》提出"阳微阴弦"为胸痹的主要病机,慢性心衰亦可从"阳微阴弦"论治,中医认为慢性心衰为本虚标实之证,以心、肾阳虚之"阳微"为本,血瘀、痰浊、水停之"阴弦"为标,其基本病机为阳微阴弦,临证时应根据"阳微"与"阴弦"之轻重、邪正之盛衰分而论之。运用系统生物学的客观检查指标及生物标志物,实现慢性心衰中医证候的客观化,为中药干预慢性心衰的治疗靶点提供客观指标。以"阳微阴弦"理论为基础,辨阴阳、辨虚实、辨病性,运用温阳、活血、祛瘀、利水类中药,循证选方,因机选药,为慢性心衰的诊治提供思路。
Based on the theory of"Yang micro Yin chord",the biomarkers of TCM syndrome of chronic heart failure and TCM intervention were discussed
Essentials of the Golden Cabinet(Jingui Yaolue)puts forward"Yang Wei Yin Xian"as the main pathogenesis of chest numbness,and chronic heart failure can also be treated from"Yang Wei Yin Xian".Traditional Chinese Medicine consid-ers chronic heart failure as the syndrome of primary deficiency and deficiency of the heart and kidney,and the"Yin Xian"of blood stasis,phlegm turbidity and water stasis as the standard.Clinical diagnosis should be based on the weight of"Yang Wei"and"Yin strings",the rise and fall of evil and positive.Objective examination indicators and biomarkers of system biology were used to achieve objectification of TCM syndromes of chronic heart failure,and to provide objective indicators for the therapeutic targets of TCM intervention in chronic heart failure.Based on the theory of"Yang Wei Yin Xian",distinguish Yin and Yang,distinguish deficiency and deficiency,distinguish disease,use herbal medicines such as warming Yang,promoting blood circula-tion,removing blood stasis and rehydrating,and select prescriptions based on evidence,to provide ideas for the diagnosis and treatment of chronic heart failure.

Heart failureYang Yin stringTCM treatment

郭瑾、王梓仪、张倩、孟骊冲、胡志希

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湖南中医药大学,湖南长沙 410208

心衰 阳微阴弦 中药治疗

国家自然科学基金广东省重点领域研发计划湖南省教育厅科技项目湖南省教育厅科技项目湖南省学位与研究生教育教学改革项目湖南省教育改革项目湖南省学位办中医诊断研究生案例库建设项目

822744122020B111110000121A023021B03612020JGZX012HNJG-2021-0594

2024

时珍国医国药
时珍国医国药杂志社

时珍国医国药

北大核心
影响因子:0.887
ISSN:1008-0805
年,卷(期):2024.35(4)
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