首页|国医大师严世芸教授治疗胸痹合并郁证的用药规律分析

国医大师严世芸教授治疗胸痹合并郁证的用药规律分析

扫码查看
目的 探析国医大师严世芸教授治疗胸痹合并郁证的用药规律。方法 收集严世芸教授于2016年5月至2023年7月在上海中医药大学附属曙光医院门诊治疗的胸痹合并郁证患者医案,录入处方。运用中医传承计算平台进行分析,同时对患者中成药的使用情况进行统计。结果 整理纳入109首处方。通过平台分析发现涉及中药177味,中药四气统计依次为温、平、寒、热、凉;五味统计依次为甘、苦、辛、酸、咸;归经统计前5位为肝、脾、肺、心、肾;中药分类统计前5位活血化瘀药类、补气药类、安神药类、补阳药类、补血药类;用药频次统计前5位的中药分别为人参、川芎、桃仁、酸枣仁、桂枝;常用的药物组合包括川芎和人参、川芎和桃仁、川芎和酸枣仁、桃仁和酸枣仁等;常用的方剂依次为酸枣仁汤、强心饮、血府逐瘀汤、补阳还五汤、柴胡桂枝龙骨牡蛎汤、瓜蒌薤白半夏汤、失笑散;中成药使用率最高的3种分别为天王补心丸、逍遥丸、归脾丸。结论 严世芸教授治疗胸痹合并郁证的用药特色以寒温并用;从肝而治,又兼顾五脏;擅用人参,补益心气;活血化瘀兼以虫类药破瘀;补益与活血化瘀并用,攻补兼施,使攻不伤正,补不助邪;时方和经方灵活组方,创制强心饮为治疗胸痹之良方;以中成药配合汤药治疗。通过展现严世芸教授辨治胸痹合并郁证的用药规律及临床经验,为治疗该病提供参考。
Analysis of the Medication Rules for Treating Chest Bi Combined with Depression Syn-drome by Renowned Traditional Chinese Medicine Master Professor YAN Shi-yun
Objective We aim to analysis the medication rules of renowned Traditional Chinese Medicine(TCM)master Profes-sor YAN Shi-yun in the treatment of chest Bi combined with depression syndrome.Methods We collect the medical records of patients with chest Bi combined with depression syndrome treated by Professor YAN Shi-yun in the outpatient department of Shu-guang Hospital affiliated to Shanghai University of TCM from May 2016 to July 2023.The prescriptions from these cases were re-corded.Subsequently,we conducted an analysis using TCM Inheritance Support Platform and performed statistical analysis on the usage of traditional Chinese patent medicines among the patients.Results In this study,a total of 109 prescriptions were includ-ed.Through analysis using the platform,it was found that 177 different Chinese herbs were involved,with their thermal properties categorized as warm,neutral,cold,hot,and cool.The taste attributes were recorded in the order of sweet,bitter,spicy,sour,and salty.In terms of the top 5 meridian affinity,including liver,spleen,lung,heart,and kidney.Furthermore,the top 5 cate-gories in the TCM classification statistics are blood-activating and stasis-resolving herbs,qi-tonifying herbs,calming the spir-it herbs,yang-tonifying herbs,and blood-nourishing herbs.The top 5 individual herbs in medication frequency are Renshen(Ginseng),Chuanxiong(Ligusticum),Taoren(Peach Kernel),Suanzaoren(Sour Jujube Seed),and Guizhi(Cinnamon Twig).The most common herbal combinations included Chuanxiong(Ligusticum)with Renshen(Ginseng),Chuanxiong(Ligus-ticum)with Taoren(Peach Kernel),Chuanxiong(Ligusticum)with Suanzaoren(Sour Jujube Seed),and Taoren(Peach Ker-nel)with Suanzaoren(Sour Jujube Seed).The frequently prescribed formulas were Suanzaoren Tang,Qiangxin Yin,Xuefu Zhuyu Tang,Buyang Huanwu Tang,Chaihu Guizhi Longgu Muli Tang,Gualou Xiebai Banxia Tang,and Shixiao San.Regarding Chinese patent medicines,the top three in terms of usage were Tianwang Buxin Wan,Xiaoyao Wan,and Guipi Wan.Conclusion Professor YAN Shi-yun's medication approach for treating chest Bi combined with depression syndrome includes the simultaneous use of cold and warm Chinese herbs,focusing on treating the liver while considering the other organs.He is skilled in using Ren-shen(Ginseng)to nourish the heart qi,and adeptly employs blood-activating herbs in combination with insect-based medi-cines to disperse stasis without harming the body.He combines tonifying and blood-activating herbs,employing both attacking and tonifying methods to ensure the attack does not damage the body and the tonification does not assist pathogenic factors.He flexibly formulates prescriptions using modified classic formulas,and he created the effective Qiangxin Yin for treating chest Bi.Chinese patent medicines are also used in combination with decoctions for treatment.By presenting Professor YAN Shi-yun's medication patterns and clinical experience in diagnosing and treating chest Bi combined with depression syndrome,this provides reference for the treatment of this condition.

Professor YAN Shi-yunChest BiDepression syndromeTCM Inheritance Support PlatformMedica-tion rules

徐朝辉、胡寅钦、柳智瑞、万琪琪、刘永明

展开 >

上海中医药大学附属曙光医院,上海 201203

安徽省中西医结合医院(上海中医药大学附属曙光医院安徽医院),安徽合肥 230011

严世芸教授 胸痹 郁证 中医传承计算平台 用药规律

国家自然科学基金西医学习中医优秀人才研修项目上海市卫生健康委科研项目安徽省卫生健康安徽省中医药局长三角名中医工作室建设项目安徽省中医药局中医优势病种诊疗能力建设项目安徽省卫生健康科研项目

81973611国中医药人教教育便函[2020]184号202340158皖中医药发展秘[2023]11号皖中医药发展秘[2023]11号AHWJ2023A20461

2024

时珍国医国药
时珍国医国药杂志社

时珍国医国药

北大核心
影响因子:0.887
ISSN:1008-0805
年,卷(期):2024.35(4)
  • 15