Clinical Observation on Treatment of Diabetic Foot Ulcer with excessive Damp-heat by Sanmiao Jiedu Liquid Fomentation
Objective To observe the clinical efficacy of Sanmiao Jiedu Liquid fomentation in treating diabetic foot ulcer with ex-cessive damp-heat.Methods Diabetic foot ulcer patients with excessive damp-heat were selected and randomly divided into observation group and control group.Both groups were given conventional basic treatment.On this basis,the observation group was treated with Sanmiao Jiedu Liquid and the control group was treated with Kangfuxin Liquid for 14 days.The general data(gender,age,course of ulcer)of the two groups were collected.Wound area,traditional Chinese medicine(TCM)syndrome score and serum TNF-α and IL-6 levels of the two groups before and after treatment were observed and compared.The efficacy and safety indexes of the two groups were evaluated.Results(1)The total effective rate of patients in the observation group after treatment was superior to that in the control group(P＜0.05).(2)The wound area of patients in the observation group after treatment was smaller than that before treatment(P＜0.05),and it was better than that in the control group(P＜0.05).(3)TCM syndrome scores of patients in the two groups after treatment were lower than those before treatment(P＜0.05),and the ob-servation group was superior to the control group(P＜0.05).The symptom scores of the two groups after treatment were all lower than those before treatment(P＜0.05).The wound pus color score,wound granulation color score and wound granulation particle score of the observation group were better than those of the control group(P＜0.05).(4)The levels of serum TNF-α and IL-6 in the two groups after treatment were lower than those before treatment(P＜0.05),and the observation group was superior to the control group(P＜0.05).No adverse events were observed in the two groups during the treatment.Conclusion Sanmiao Jiedu Liquid fomentation can improve the local symptoms of limbs in diabetic foot ulcer patients with excessive damp-heat,pro-mote wound healing,and reduce serum TNF-α and IL-6 levels.
Diabetic foot ulcerSanmiao Jiedu LiquidChinese medicine fomentationClinical observation
NETL
NSTL
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