Meta-analysis of the efficacy of traditional Chinese medicine on male infertility patients
Objective To observe and evaluate the therapeutic effect of traditional Chinese medicine on male infertility patients by Meta analysis.Methods Chongqing VIP Chinese Science and Technology Journal Database(VIP),China National Knowledge Infrastructure(CNKI),China Academic Journal Database(Wanfang Data),Pubmed,EMbase,Cochrane Library were searched by computer.The time from the beginning to the end was from the establishment of each database to December 1,2022.Randomized controlled trials(RCTs)of traditional Chinese medicine and Western medicine in the treatment of male infertility were collected.Two researchers screened the literature according to the inclusion and exclusion criteria,and included the relevant information in the literature.Meta-analysis was performed using REVMAN5.4.1 software.Results A total of 22 articles on the treatment of male infertility were included.The results of meta-analysis of 1879 cases showed that.Total effective rate[RD=0.22,(95％CI:0.18～0.26),P＜0.01],sperm DNA fragmentation rate[MD=-5.84,(95％CI:-6.99～4.69),P＜0.01],total sperm motility[MD=5.90,(95％CI:3.68～8.15),P＜0.01],sperm concentration[MD=7.37,(95％CI:4.65～10.1),P＜0.01],percentage of forward motile sperm[MD=7.50,(95％CI:5.91～9.08),P＜0.01].Conclusion Traditional Chinese medicine can significantly reduce sperm DNA damage,improve total ef-fective rate and total sperm motility,and improve sperm concentration,forward movement sperm percentage and other indicators,which has a good therapeutic effect on male infertility.
Sperm DNA damageSperm analysis parametersTraditional Chinese medicineMeta analysisMale infertility
NETL
NSTL
万方数据
