Efficacy Evaluation of Qinjiao Pill Combined Pricking and Cupping in the Treatment of Psoriasis(blood-heat syndrome)and Its Influence on Serum Inflammatory Factors
Objective To explore the clinical efficacy of Qinjiao Pill combined with pricking and cupping in the treatment of blood-heat syndrome of psoriasis and the interventional effects on serum inflammatory factors.Methods 130 patients with psoriasis with blood-heat syndrome who were admitted to the outpatient clinic of the dermatology department of the hospital from October 2021 to October 2023 were selected and randomly divided into 65 cases each in the treatment group and the control group.The treatment group was given Chinese herbal medicine soup Qinjiao Pill plus reduction combined with Chinese medicine characteristic external treatment pricking and cupping therapy.The control group was given only pricking and cupping therapy.PASI scores of skin lesions,DLQI index scores of quality of life,and scores of Chinese medicine evidence were recorded before treatment,at the 2nd week and at the 4th week in both groups,and the levels of tumor necrosis factor-α(TNF-α),interferon-gamma(INF-γ),interleukin-6(IL-6),and interleukin-17(IL-17)were detected by ELISA before and after the treatment in patients'blood serum.Results The total effective rate of 96.92％in the treatment group was significantly higher than 83.08％in the con-trol group(P＜0.05).The PASI score,quality of life DLQI index,and Chinese medicine evidence score of the two groups were significantly reduced after treatment.The levels of serum inflammatory factors TNF-α,INF-γ,IL-6 and IL-17 in both groups were significantly improved compared with those before treatment,and the scores of the treatment group were significantly better than those of the control group,with statistically significant differences(P＜0.05).Conclusion Qinjiao Pill combined with pricking and cupping can effectively improve the skin lesions and Chinese medicine symptoms of patients with psoriasis with blood-heat syndrome,reduce the level of inflammatory factors and improve the quality of life of patients.The therapeutic effect is accurate,showing the characteristic therapeutic advantages of traditional Chinese medicine,and it is worth to be popularized and used in clinical practice.
Qinjiao PillPricking and CuppingBlood-heat syndrome psoriasisInflammatory factor
NETL
NSTL
万方数据
