Effect of Bushen Huoxue Formula Combined with Core Stability Training in Improving Clini-cal Symptoms and Fat Content of Paravertebral Multifidus in Elderly Patients with Chronic Non-specific Low Back Pain
Objective To study the effect of Bushen Huoxue Formula combined with core stability training(CST)on the clinical symp-toms and fat content of paravertebral multifidus muscle in elderly patients with chronic non-specific low back pain(CNLBP).Methods A total of 84 elderly patients with CNLBP were selected and divided into control group and observation group according to simple random method.The patients in both groups underwent CST under the guidance of professional rehabilitation therapists,in which the patients in the observation group were orally treated with Bushen Huoxue Formula on this basis.Patients in both groups were treated for 12 w.The changes in low back pain symptoms,fat content of the multifidus muscle adjacent to each lumbar vertebral segment,electromyographic signals on the surface of the multifidus muscle,levels of pain associated with inflammatory mediators,and gait kinetic parameters were compared between the two groups before and after treatment.Results The VAS of the patients in the observation group was significantly lower than that of the control group at 4 w and 12 w(P＜0.05).After treatment,the L2～5 parasegmental polyfidus muscle fat content of each lumbar vertebrae,interleukin-1 β(IL-1 β)level,the initial double brace,single brace phase and final double brace vertical Ground Reaction Force(vGRF)in the observation group were significantly lower than those in the control group(P＜0.05).After treat-ment,the flexion-relaxation ratio during extension(EXT/MVF),flexion-relaxation ratio during flexion(FLEX/MVF),and β-en-dorphins(β-EP)level in the observation group were higher than those in the control group(P＜0.05).Conclusion The combination of Bushen Huoxue Formula combined with CST can effectively improve the clinical symptoms of elderly patients with CNLBP,reduce the fat content of paravertebral bifidus muscle,and improve the quality of life.
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