Objective To establish a High Performance Liquid Chromatography(HPLC)method for determining the multi-component contents and fingerprint chromatography of Chenxiang Lubailu Tablet(CLT).Methods HPLC was used to determine the content of ef-fective components and establish the fingerprints of 17 batches of CLT.The mobile phase was acetonitril-methanol-0.1%phosphoric acid water,gradient elution,and the detection wavelength was 230nm.Results The HPLC method was established to determine the con-tents and fingerprint analysis of CLT.The peak separations of liquiritin,hesperidin,ammonium glycyrrhizinate,β-asarum ether,cost-unolide and dehydrocostus lactone in the specific tests were all greater than 1.5.The similarity between the corresponding fingerprint and the control fingerprint was greater than 0.9.Conclusion The method of fingerprint and determination of six components of CLT is sim-ple,accurate and reliable,which can be used for the quality control of CLT.
维普
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