Meta-Analysis of Acupuncture and Moxibustion in the Treatment of Schizophrenia
Objective To evaluate the effect of acupuncture and moxibustion on positive classification of mental disorders.Methods Literature related to acupuncture and moxibustion for the treatment of schizophrenia was searched from all aspects in major medical literature databases at home and abroad. Research literature was included according to the principles and means of evidence-based medicine, and meta-analysis was performed. Results After comprehensive screening, it was found that 17 literatures were finally selected. Meta-analysis results: (1) in terms of total effective rate, heterogeneity test of literature research results: Chi=14.26, freedom is 16, P=0.58, 12= 0％. It was considered that the studies were qualitative. When the combined OR value is 3.09, the 95％ confidence interval is [2.31, 4.13], and the combined effect test Z=7.62, P<0.000 01. The diamond lies to the right of the line. In terms of adverse reactions, the binary variable study showed that the OR value after combination was 0.34, and the 95％ confidence interval was [0.16, 0.75]. The combined effect test z=2.67, P=0.008. The diamond is to the left of the line. For continuous variables, the combined SMD value was-0.91, and the 95％ confidence interval was [-0.88, -0.34]. The combined effect test z=4.39, P<0.000 1. Conclusion According to the existing research data at home and abroad, the therapeutic effect of acupuncture combined with conventional antipsychotic drugs in the treatment of schizophrenia is significantly lower than that of antipsychotic drugs alone, and the incidence of adverse reactions is also significantly lower. Rigorous and careful experimental design is still required. High-quality clinical studies with large sample size provide more reliable basis for the following analysis.
Acupuncture and moxibustionSchizophreniaEvidence-based medicineMeta-analysisMeta
NETL
NSTL
万方数据
维普
