首页|基于负压封闭引流技术应用三黄汤灌注治疗体表脓肿的临床研究

基于负压封闭引流技术应用三黄汤灌注治疗体表脓肿的临床研究

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目的:观察负压封闭引流技术(VSD)联合三黄汤灌注对体表脓肿创面的治疗效果。方法:选取临沂市人民医院烧伤整形科2013年6月至2017年2月期间收治的72例体表脓肿患者,采用随机数字表法随机分为3组,单纯中药组、单纯VSD组、联合组,各24例。单纯中药组患者仅采用三黄汤持续外敷,单纯VSD组患者仅采用0。9%氯化钠注射液和VSD持续灌注冲洗,联合组患者采用三黄汤和VSD持续灌注冲洗。观察各组患者不同时间段创面创腔面积缩小率、创面肉芽生长情况、疼痛程度及炎症相关检查等指标。结果:在清创后首次拆除VSD或清创后第5天、清创后第 10 天和清创后第 15 天,联合组患者创面创腔面积缩小率均大于单纯中药组和单纯VSD组,差异具有统计学意义(P<0。05)。在清创后首次拆除VSD或清创后第 5 天、清创后第 10 天和清创后第 15 天,联合组患者在创面肉芽生长评分方面高于单纯中药组和单纯VSD组,差异具有统计学意义(P<0。05)。清创后第10天和第15天,联合组患者VAS评分均低于单纯中药组和单纯VSD组,差异具有统计学意义(P<0。05)。清创后第5天、第10天和第 15 天联合组患者的白细胞(WBC)计数、C反应蛋白(CRP)水平、红细胞沉降率(ESR)均低于单纯中药组和单纯VSD组,差异具有统计学意义(P<0。05)。结论:三黄汤联合VSD促进创面愈合效果优于单纯应用三黄汤外敷或单纯VSD,为体表脓肿提供了一种简单可行的治疗方法。
Clinical Study on the Treatment of Superficial Abscess with Sanhuang Decoction Based on Vacuum Sealing Drainage
Objective To observe the therapeutic effect of vacuum sealing drainage(VSD)combined with Sanhuang decoction perfusion on superficial abscess wound.Methods A total of 72 patients with body surface abscess admitted to the Department of Burn and Plastic Surgery of Linyi People's Hospital from June 2013 to February 2017 were randomly divided into three groups by random number table method:simple Chinese medicine group,simple VSD group and combined group,with 24 cases in each group.Patients in the simple Chinese medicine group were only given continuous external application of Sanhuang decoction,patients in the simple VSD group were only given continuous perfusion irrigation of 0.9%sodium chloride solution and VSD,and patients in the combined group were given continuous perfusion irrigation of Sanhuang decoction and VSD.The reduction rate of wound area,the growth of wound granulation,the degree of pain and the examination of inflammation were observed.Results After VSD removal for the first time after debridement or on the 5th,10th and 15th days after debridement,the reduction rate of wound cavity area in the combined group was higher than those in the simple Chinese medicine group and the simple VSD group,the differences were statistically significant(P<0.05).After VSD removal for the first time after debridement or on the 5th,10th and 15th days after debridement,the wound granulation growth score of the combined group was higher than those of the simple Chinese medicine group and the simple VSD group,the differences were statistically significant(P<0.05).On the 10th and 15th days after debridement,the visual analogue scale(VAS)scores in the combined group were lower than those in the simple Chinese medicine group and the simple VSD group,and the differences were statistically significant(P<0.05).The white blood cell(WBC),C-reactionprotein(CRP)and erythrocyte sedimentation rate(ESR)of the combined group were lower than those of the simple Chinese medicine group and the simple VSD group on the 5th,10th and 15th days after dedebrination,and the differences were statistically significant(P<0.05).Conclusion The effect of Sanhuang decoction combined with VSD in promoting wound healing is better than that of simple application of Sanhuang decoction or simple VSD,which provides a simple and feasible treatment method for body surface abscess.

Superficial abscessSanhuang decoctionVacuum sealing drainage

刘荣朋、付妍婕、白南、陈远征、苏伟

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临沂市人民医院,山东 临沂 276000

应急总医院,北京 100028

体表脓肿 三黄汤 负压封闭引流技术

山东省自然科学基金山东省中医药科技项目

ZR2021MH3382020M170

2024

深圳中西医结合杂志
深圳市中西医结合临床研究所

深圳中西医结合杂志

影响因子:0.692
ISSN:1007-0893
年,卷(期):2024.34(2)
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