首页|南阳市口腔医院2021-2022年口腔疾病患者病原菌感染及耐药性分析

南阳市口腔医院2021-2022年口腔疾病患者病原菌感染及耐药性分析

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目的:分析南阳市口腔医院 2021-2022 年口腔疾病患者的病原菌分布特征及其耐药性。方法:选取2021 年 1 月至 2022 年 12 月南阳市口腔医院收治的口腔疾病患者 179 例,采集患者口腔分泌物,进行病原菌培养和药敏试验,分析病原菌分布特征和耐药性。结果:179 例口腔疾病患者,共分离出 58 株病原菌;革兰阴性菌 17 株,占比 29。31%,以铜绿假单胞菌(5。17%)、肺炎克雷伯菌(8。62%)为主;革兰阳性菌 41 株,占比 70。69%,以表皮葡萄球菌(13。79%)、星群链球菌星群亚种(20。69%)为主。铜绿假单胞菌对阿米卡星、庆大霉素、妥布霉素耐药率较高,对环丙沙星、他唑巴坦、多黏菌素B及头孢他啶耐药性均为 0。00%;肺炎克雷伯菌对阿米卡星、舒巴坦、环丙沙星、庆大霉素、妥布霉素及头孢他啶耐药率较高,对他唑巴坦、多黏菌素B均为 0。00%。表皮葡萄球菌对阿奇霉素、红霉素、青霉素耐药率较高,星群链球菌星群亚种对达托霉素、美罗培南、利奈唑胺、青霉素、氯霉素及利福平无耐药性,表皮葡萄球菌对达托霉素、美罗培南、利奈唑胺、利福平无耐药性。结论:南阳市口腔医院2021-2022 年口腔疾病患者病原菌感染种类较多,主要以革兰阳性为主,临床需参照病原菌检测结果,结合病原菌耐药状况,挑选合理的抗菌药物进行抗感染治疗。
Analysis of Pathogenic Bacterial Infection and Drug Resistance in Patients with Oral Diseases in Nanyang Stomatological Hospital From 2021 to 2022
Objective To analyze the distribution characteristics and drug resistance of pathogens in oral disease patients at Nanyang Stomatological Hospital from 2021 to 2022.Methods A total of 179 patients with oral diseases admitted to Nanyang Stomatological Hospital from January 2021 to December 2022 were selected to collect oral secretions of patients,the pathogen culture and drug sensitivity test were conducted,and the distribution characteristics and drug resistance of pathogens were analyzed.Results Fifty-eight strains of pathogenic bacteria were isolated from 179 patients with oral diseases.There were 17 Gram-negative bacteria,accounting for 29.31%,mainly Pseudomonas aeruginosa(5.17%)and Klebsiella pneumoniae(8.62%).There were 41 strains of Gram-positive bacteria,accounting for 70.69%,mainly Staphylococcus epidermidis(13.79%)and Streptococcus asterae subspecies(20.69%).The resistance rate of Pseudomonas aeruginosa to amicacin,gentamicin and tobramycin was high,and the resistance rate to ciprofloxacin,tazobactam,polymyxin B and ceftazidme was 0.00%.The resistance rate of Klebsiella pneumoniae to amikacin,sulbactam,ciprofloxacin,gentamicin,tobramycin and ceftazidime was higher,to tazobactam and polycolistin B was 0.00%.Staphylococcus epidermidis had high resistance rate to azithromycin,erythromycin and penicillin.Streptococcus asteroidis subspecies had no resistance to dattomycin,meropenem,linezolid,penicillin,chloramphenicol and rifampicin.Staphylococcus epidermidis had no resistance to dattomycin,meropenem,linezolid and rifampicin.Conclusion From 2021 to 2022,there were many types of pathogenic bacterial infections in patients with oral diseases at Nanyang Stomatological Hospital,mainly Gram-positive.Clinically,it is necessary to refer to the results of pathogenic bacterial testing and select reasonable antibiotics for anti infection treatment based on the resistance status of pathogenic bacteria.

Oral diseasesPathogenic bacteria distributionDrug resistance analysis

龚欣、史德莹、祝宏伟、汤晓雨

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南阳市口腔医院,河南 南阳 473000

口腔感染 病原菌分布 耐药性分析

南阳市科技计划

KJGG175

2024

深圳中西医结合杂志
深圳市中西医结合临床研究所

深圳中西医结合杂志

影响因子:0.692
ISSN:1007-0893
年,卷(期):2024.34(3)
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