首页|近十年中医药治疗三阴性乳腺癌研究的可视化分析-基于CiteSpace知识图谱

近十年中医药治疗三阴性乳腺癌研究的可视化分析-基于CiteSpace知识图谱

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目的:从近十年三阴性乳腺癌(TNBC)中医药研究文献中,探究其研究轨迹与发展动向。方法:在中国知网(CNKI)中对2013年1月1日至2023年12月1日的中医药领域TNBC治疗文献进行检索,利用CiteSpace 6。2软件从文献的关键词、作者及机构等方面进行可视化分析。结果:近十年中医药领域治疗TNBC文献发文量呈增长态势。合作网络关键词共线及聚类分析中发现,TNBC中医药研究主要聚焦在细胞凋亡、化疗、增殖、转移、免疫及生存质量方面,而分子对接是新出现的研究热点,突现分析提示细胞自噬是近五年出现的热点。文献发文量最多的作者是刘胜。发文量最多的研究机构是北京中医药大学。结论:关于TNBC的中医药研究处于上升阶段。目前研究热点主要集中在中医药应用提升TNBC患者免疫功能、提高生活质量、辅助化疗和细胞增殖凋亡机制。而分子对接和细胞自噬是新出现的研究前沿,值得进一步研究与挖掘。
Visual Analysis of Traditional Chinese Medicine Treatment for Triple-Negative Breast Cancer Research Over the Past Decade-Based on CiteSpace Knowledge Mapping
Objective To explore the research trajectory and development trends in Traditional Chinese Medicine(TCM)studies on triple-negative breast cancer(TNBC)from the recent literature over the past decade.Methods Searching-work was conducted in the China National Knowledge Infrastructure(CNKI)database for literature on the treatment of TNBC with TCM from January 1,2013,to December 1,2023.CiteSpace 6.2 software was utilized for visual analysis of the literature's keywords,authors,and institutions.Results The publication volume of TCM literature on TNBC treatment has shown an increasing trend over the past ten years.Co-word and cluster analysis of the collaboration network revealed that TCM research on TNBC mainly focuses on apoptosis,chemotherapy,proliferation,metastasis,immunity,and quality of life,with molecular docking emerging as a new research hotspot.Burst analysis indicated that autophagy has become a hotspot in the past five years.The author with the highest publication volume is Liu Sheng,and the institution with the most publications is Beijing University of Chinese Medicine.Conclusion TCM research on TNBC is in a rising phase.Current hotspots mainly concentrate on the application of TCM to enhance immune function in TNBC patients,improve quality of life,aid chemotherapy,and elucidate mechanisms of cell proliferation and apoptosis.Molecular docking and autophagy represent new frontiers in research that warrant further exploration and investigation.

Traditional Chinese MedicineTriple Negative Breast CancerCiteSpaceKnowledge Mapping

简文静、岳双冰、卓超林、张广路、宋亚中、金宇

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深圳市第二人民医院,广东 深圳 518035

三阴性乳腺癌 中医药 CiteSpace 知识图谱

广东省自然科学基金广东省高水平医院人才培育经费资助

2018A03031000234004017

2024

深圳中西医结合杂志
深圳市中西医结合临床研究所

深圳中西医结合杂志

影响因子:0.692
ISSN:1007-0893
年,卷(期):2024.34(5)
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