Analysis of the Level of Vitamin D in Patients with COVID-19 in Shenzhen
Objective To analyse the level of vitamin D in patients with coronavirus disease 2019(COVID-19)in Shenzhen Third People's Hospital.The hospital is the designated medical institution for patients with COVID-19 in Shenzhen.Methods Serum level of 25-hydroxyvitamin D[25(OH)D]was measured in patients with COVID-19 from 13 December 2021 to 25 February 2022.The patients were admitted to Shenzhen Third People's Hospital with COVID-19.Their level of 25(OH)D was compared between different age and gender groups,and with those of the population who underwent a physical examination in Guangdong province.Results There was no statistically significant difference in the level of 25(OH)D between men and women of COVID-19 in Shenzhen(P>0.05).The level of 25(OH)D in the age group<30 years was the lowest,and the level of 25(OH)D in the age group 40-49 years was the highest.There was a statistically significant difference between the groups(P<0.05).The average serum level of 25(OH)D patients with COVID-19 in Shenzhen was(54.13±14.80)nmol·L-1,which was lower than that of people with physical examination in Guangdong,with a statistically significant difference(P<0.05).And the vitamin D adequacy rate of COVID-19 people(8.7%)was lower than that of the people who were examined(25.9%),with a statistically significant difference(P<0.05).Conclusion The level of vitamin D in people with COVID-19 in Shenzhen were generally low,and lower than the level of the physical examination population in Guangdong,with a large number of deficiencies and insufficiencies,especially in the<30 years old age group.There is a possibility that the level of vitamin may be correlated with the incidence of COVID-19.Considering that vitamin D has multiple correlations with health,appropriately increasing the level of vitamin D maybe have a positive effect on health.
COVID-1925-hydroxyvitamin DPhysical examination population