首页|重复经颅磁刺激治疗缺血性脑卒中后认知功能障碍的疗效观察

重复经颅磁刺激治疗缺血性脑卒中后认知功能障碍的疗效观察

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目的:探究缺血性脑卒中后认知功能障碍干预中重复经颅磁刺激治疗的效果。方法:回顾性选取2022 年 7 月至 2023 年 6 月郑州大学第五附属医院收治的 60 例缺血性脑卒中后认知功能障碍患者,依据干预方法的不同分为常规性认知康复训练组、重复经颅磁刺激治疗组两组,各30例。常规性认知康复训练组进行认知康复训练,重复经颅磁刺激治疗组在认知康复训练基础上进行重复经颅磁刺激治疗。比较两组患者认知功能、神经功能、生存质量、临床疗效、不良反应发生情况。结果:干预后,重复经颅磁刺激治疗组患者蒙特利尔认知评估量表(MoCA)评分、认知评定量表(CRS)评分、脑卒中专门化生存质量量表(SS-QOL)各项评分及总分均高于常规性认知康复训练组,差异具有统计学意义(P<0。05)。干预后,重复经颅磁刺激治疗组患者美国国立卫生研究院脑卒中量表(NIHSS)评分低于常规性认知康复训练组,差异具有统计学意义(P<0。05)。重复经颅磁刺激治疗组患者临床总有效率高于常规性认知康复训练组,差异具有统计学意义(P<0。05)。两组患者不良反应发生率比较,差异无统计学意义(P>0。05)。结论:缺血性脑卒中后认知功能障碍干预中认知康复训练基础上联合重复经颅磁刺激治疗的效果较单独应用认知康复训练显著。
Observation on the Therapeutic Effect of Repeated Transcranial Magnetic Stimulation on Cognitive Dysfunction after Ischemic Stroke
Objective To explore the efficacy of repeated transcranial magnetic stimulation treatment in cognitive dysfunction intervention after ischemic stroke.Methods A retrospective selection was conducted on 60 patients with cognitive dysfunction after ischemic stroke admitted to the Fifth Affiliated Hospital of Zhengzhou University from July 2022 to June 2023.According to different intervention methods,they were divided into two groups,conventional cognitive rehabilitation training group and repeated transcranial magnetic stimulation treatment group,with 30 cases in each group.The conventional cognitive rehabilitation training group received cognitive rehabilitation training,while the repeated transcranial magnetic stimulation treatment group received repeated transcranial magnetic stimulation treatment on the basis of cognitive rehabilitation training.The cognitive function,neurological function,quality of life,clinical efficacy and occurrence of adverse reactions were compared between the two groups.Results After intervention,the scores of Montreal cognitive assessment scale(MoCA),cognitive rating scale(CRS),and the stroke specific quality of life scale(SS-QOL)and the total scores of patients in the repeated transcranial magnetic stimulation treatment group were higher than those in the conventional cognitive rehabilitation training group,with statistical significance(P<0.05).After intervention,the National Institutes of Health stroke scale(NIHSS)score of patients in the repeated transcranial magnetic stimulation treatment group was lower than that in the conventional cognitive rehabilitation training group,and the difference was statistically significant(P<0.05).The total clinical effective rate of patients in the repeated transcranial magnetic stimulation treatment group was higher than that in the conventional cognitive rehabilitation training group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups of patients(P>0.05).Conclusion In the intervention of cognitive dysfunction after ischemic stroke,the combination of cognitive rehabilitation training and repeated transcranial magnetic stimulation treatment has a significant therapeutic effect compared to the use of cognitive rehabilitation training alone.

Ischemic strokeCognitive dysfunctionRepeated transcranial magnetic stimulation

王国胜、梁英姿、方明珠

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郑州大学第五附属医院,河南 郑州 450052

缺血性脑卒中 认知功能障碍 重复经颅磁刺激

河南省医学科技攻关计划(联合共建)项目

LHGJ20190431

2024

深圳中西医结合杂志
深圳市中西医结合临床研究所

深圳中西医结合杂志

影响因子:0.692
ISSN:1007-0893
年,卷(期):2024.34(9)