首页|银杏叶提取物联合丁苯酞治疗急性脑梗死的临床效果观察

银杏叶提取物联合丁苯酞治疗急性脑梗死的临床效果观察

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目的:分析银杏叶提取物注射液联合丁苯酞氯化钠注射液治疗急性脑梗死(ACI)的临床效果,以及对患者血液指标及神经缺损程度的影响。方法:选取郑州市金水区总医院 2022 年 1 月至 2024 年 1 月收治的ACI患者80 例作为研究对象,以随机数字表法分为对照组(40 例,丁苯酞氯化钠注射液治疗)及观察组(40 例,银杏叶提取物注射液联合丁苯酞氯化钠注射液治疗)两组。治疗 14 d后,比较两组患者治疗前后神经缺损程度、血液指标、炎症因子指标变化以及药物相关不良反应发生情况。结果:治疗 14 d后,相比于对照组,观察组患者神经缺损程度评分、红细胞压积及纤维蛋白原、D-二聚体、C反应蛋白水平均较低,差异具有统计学意义(P<0。05)。两组患者药物相关不良反应发生率比较,差异无统计学意义(P>0。05)。结论:ACI选择银杏叶提取物注射液、丁苯酞氯化钠注射液联合治疗方案,能够切实改善凝血功能、血液指标,缓解炎症反应,降低神经缺损程度,提升自理能力,药物安全性理想。
Clinical Observation of Ginkgo Biloba Extract Combined with Sodium Butylphthalide in the Treatment of Acute Cerebral Infarction
Objective To analyze the clinical effect of ginkgo biloba extract injection combined with butylphthalide sodium chloride injection in the treatment of acute cerebral infarction(ACI),and the influence on blood indexes and nerve defect degree of patients.Methods A total of 80 ACI patients admitted to Zhengzhou Jinshui District General Hospital from January 2022 to January 2024 were selected as the study objects,and were divided into two groups by random number table method:the control group(40 cases treated with butylphthalide sodium chloride injection)and the observation group(40 cases treated with ginkgo biloba extract injection combined with butylphthalide sodium chloride injection).After 14 days of treatment,the degree of nerve defect,blood indexes,inflammatory factor indexes and the occurrence of drug-related adverse reactions were compared between the two groups before and after treatment.Results After 14 days of treatment,the nerve defect score,the levels of hematocrit,fibrinogen,D-dimer and C-reactive protein in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of drug-related adverse reactions between the two groups(P>0.05).Conclusion The combination treatment of ginkgo biloba extract injection and butylphthalide sodium chloride injection for ACI can effectively improve coagulation function and blood indexes,relieve inflammation,reduce nerve defects,improve self-care ability,and provide ideal drug safety.

Acute cerebral infarctionGinkgo biloba extract injectionButylphthalide sodium chloride injection

崔植梁、张华民、段春燕

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郑州市金水区总医院,河南 郑州 450000

急性脑梗死 银杏叶提取物注射液 丁苯酞氯化钠注射液

2024

深圳中西医结合杂志
深圳市中西医结合临床研究所

深圳中西医结合杂志

影响因子:0.692
ISSN:1007-0893
年,卷(期):2024.34(16)