Objective To analyze the impact of high-dose methylprednisolone combined with intravenous azithromycin on symptom improvement time,inflammatory indicators,and absorption of pulmonary imaging lesions in children with Mycoplasma pneumonia causing multiple lung lobe infiltration.Methods A total of 80 children with Mycoplasma pneumonia and multiple lung lobe infiltration who were treated at Dongguan Hengli Hospital from January 2022 to January 2024 were selected as the research subjects and randomly divided into an observation group and a control group,with 40 cases in each group.Patients in the control group were treated with intravenous azithromycin,while patients in the observation group were additionally treated with high-dose methylprednisolone.The time to symptom improvement,inflammatory indicators,and the rate of absorption of pulmonary imaging lesions were compared between the two groups.Results The time for symptoms to disappear in the observation group was shorter than that in the control group,with statistically significant differences(P＜0.05).After treatment,the levels of white blood cell count(WBC),neutrophil count(NEUT),serum C-reactive protein(CRP),serum amyloid A(SAA),and interleukin-6(IL-6)in the observation group were lower than those in the control group,with statistically significant differences(P＜0.05).The total effective rate of treatment in the observation group was higher than that in the control group,with a statistically significant difference(P＜0.05).Conclusion The use of high-dose methylprednisolone combined with azithromycin is effective in the treatment of children with Mycoplasma pneumonia with multiple lung lobe infiltration,effectively improving the levels of inflammatory indicators.
万方数据
维普
