Objective To compare the effects of remimazolam and propofol induction in patients undergoing total knee arthroplasty(TKA).Methods A retrospective analysis was conducted on 120 TKA patients admitted to Mindong Hospital of Ningde City from March 2022 to March 2024.Patients were divided into a control group and an observation group according to different anesthesia induction regimens,with 60 cases in each group.Patients in the control group received propofol for anesthesia induction,while patients in the observation group received remimazolam for anesthesia induction.Hemodynamic parameters and the incidence of restlessness at different time points were compared between the two groups.Results At the time of anesthesia induction(T1),after tracheal intubation(T2),and 5 minutes after the start of surgery(T3),the heart rate(HR)and mean arterial pressure(MAP)in the observation group were higher than those in the control group,with statistically significant differences(P＜0.05).There was no statistically significant difference in bispectral index between the two groups from before anesthesia induction(T0)to after extubation(T4)(P＞0.05).The incidence of restlessness in the observation group was 3.33%,which was lower than 21.67%in the control group,with statistically significant difference(P＜0.05).Conclusion Compared to propofol,remimazolam has better hemodynamic stability effect in anesthesia induction for TKA patients and can significantly reduce the incidence of restlessness,with higher safety profile.
关键词
全膝关节置换术/瑞马唑仑/丙泊酚/老年人
Key words
Total knee arthroplasty/Remimazolam/Propofol/Elderly people
维普
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