In this paper,the Y2O3-Sc2O3-ZrO2 solid solution powders were prepared by sol-gel combustion method,meanwhile the effects of ZrO2 as well as hot pressing sintering parameters on the micro-structure and properties of the Y2O3-Sc2O3-ZrO2 solid solution transparent ceramics were studied.The results showed that the grain sizes of nanopow-ders decreased with the increase of ZrO2 doping amount.In the process of hot pressing sintering,ZrO2 can effectively in-hibit the migration of grain boundaries and enhance the density,infrared transmission,strength and toughness of the ce-ramic.Under the optimized condition of temperature of 1 300℃ with holding time of 30 min and pressure of 40MPa,the obtained Y2O3-Sc2O3-ZrO2 ceramic exhibited the best comprehensive performance,i.e.its average grain size was only 94 nm,relative density was 98.5%,Vickers hardness was 10.44 GPa,fracture toughness was 1.42 MPa·m1/2,and the maximum transmittance within 3~6 μm was 72% .