Study on the Preparation and Antioxidant Activity in Vitro of Polysaccha-ride Effervescent Granules from Physalis pubescens
The aim of this study is to prepare polysaccharides effervescent granules of Physalis pubescens and determine its antioxidant ca-pacity.Response surface methodology was used to screen the best prescription of effervescent granules and evaluate its quality.The content of polysaccharide in the preparation was determined by phenol-concentrated sulfuric acid detection method.The antioxidant capacity was also measured.The results showed that the best prescription was 15％polysaccharide powder of pilose acid pulp,the mass ratio of sodium bicarbonate to citric acid was 1∶1.1,the mass ratio of polyethylene glycol 6000 to sodium bicarbonate was 0.3∶1,the diluent was mannitol with a mass ratio of 30％,the adhesive was PVP-K30 ethanol solution with a mass ratio of 6.4％.The polysaccharide effervescent granules of Physalis pubescens have certain reducing power,and its mass concentration is positively correlated with the reducing power;when the concentration is 1.0 mg/mL,the removal rate of·OH reaches 85.66％;when the concentration is 4.0 mg/mL,the scavenging rate of DPPH free radical reaches 83.45％;when the concentration is 4.0 mg/mL,the removal rate of superoxide anion reaches 25.88％.The polysaccharide effervescent granules of Physalis pubescens is convenient to take,suitable in taste,and has good antioxidant activity.
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