Chemical Constituents of n-Butanol Extract from America Ginseng Berry
Absrtact:To study the chemical constituents from the n-Butanol extract from American ginseng berry,the n-Butanol extract from American ginseng berry was separated and purefied by the silica gel,MCI and RP-C18 column chromatographies,along with semi-preparative HPLC.The structures of compounds were identified by the spectroscopic analysis,and compared with the literature values.Twenty-five ginseno-sides isolated from American ginseng berry were identified as ginsenoside Rg6(1),ginsenoside Rh2(2),20(22)E-ginsenoside Rh4(3),pseu-doginsenoside RT5(4),ginsenoside Rh1(5),20(R)-ginsenoside Rh1(6),ginsenoside F1(7),pseudoginsenoside F11(8),ginsenoside Rg1(9),ginsenoside Rg2(10),20(R)-ginsenoside Rg2(11),ginsenoside F2(12),ginsenoside Rg3(13),20(R)-ginsenoside Rg3(14),ginsenoside Re(15),ginsenoside Rs3(16),ginsenoside Rc(17),ginsenoside Rd(18),ginsenoside Rb1(19),ginsenoside Rb2(20),ginsenoside Rb3(21),gin-senoside Ro(22),gypenoside Ⅶ(23),notoginsenoside R1(24),and notoginsenoside Fe(25),respectively.Compounds 1,3,6,11,12,16 and 23~25 were isolated from American ginseng berry for the first time,and compounds 1,3,16 and 24 were isolated from American ginseng for the first time.This study could provide a chemical basis for the comprehensive development and utilization of American ginseng.
American ginseng berryn-butanol extractchemical constituent