摘要
哈蟆油是我国吉林省道地药材,现代医学称其为"绿色软黄金",被定为国家二级保护中药材,具有补肾益精、养阴润肺之功效,常用于病后体弱,神疲乏力,心悸失眠,盗汗,痨嗽咳血等病症的治疗.哈蟆油主要含有多糖、蛋白质、氨基酸、脂肪酸、甾体、类固醇、磷脂、核苷、维生素、矿物质元素等化学成分.本研究对哈蟆油的化学成分和药理作用进行归纳总结,同时结合质量标志物的概念理论,发现30余种可作为哈蟆油质量控制的潜在质量标志物,为进一步提升哈蟆油质量评价体系提供参考,助力哈蟆油高质量发展.
Abstract
Oviductus Ranae is a genuine medicinal herb in Jilin Province,China,known as"green soft gold"in modern medicine.It has been designated as a national second level protected Chinese medicinal herb and has the effects of tonifying the kidney,nourishing essence,nour-ishing yin and moistening the lungs.It is commonly used for the treatment of symptoms such as weakness,fatigue,palpitations,insomnia,night sweats,tuberculosis,cough and blood.It mainly contains chemical components such as polysaccharides,proteins,amino acids,fatty acids,steroids,phospholipids,nucleosides,vitamins,mineral elements,etc.This study summarized the chemical composition and pharmac-ological effects of Oviductus Ranae,and combined the concept theory of quality markers to discover more than 30 potential quality markers that can be used for quality control of Oviductus Ranae.This provides reference for further improving the economic efficiency and quality evaluation system of Oviductus Ranae production,and helps to promote the high-quality development of Oviductus Ranae.
基金项目
国家重点研发计划项目(2021YFD1600903)
省级大学生创新创业项目(S202210199011X)