The complex system of traditional Chinese medicine is composed of multiple bioactive components,which exert therapeutic ef-fects through complex interactions in vivo and in vitro.With the development of science and technology,multi-omics analysis technology has become an important tool to study the complex system of traditional Chinese medicine.Multi-omics analysis techniques,including geno-mics,proteomics,metabolomics,etc.,can comprehensively reveal the mechanism of action of TCM components at the molecular level,and provide new perspectives and methods for the modernisation research and clinical application of TCM.This review focuses on summarising the overview of the complex system of TCM,the utility of different histological analysis techniques,the advantages of multi-omics analysis techniques in the analysis of pharmacodynamics,molecular level elucidation,therapeutic efficacy and safety of the complex system of TCM,and exploring the optimisation strategies of the interdisciplinary intersection of TCM and molecular biology for the in-depth development of the complex system of TCM,in order to promote the in-depth development of the complex system of TCM.
关键词
中药复杂体系/多组学分析/基因组学/蛋白质组学/代谢组学
Key words
complex system of traditional Chinese medicine/multi-omics analysis/genomics/proteomics/metabolomics