Study on the status of financial toxicity and its impact on quality of life in patients with breast cancer
Objective:To explore the current status of financial toxicity in patients with breast cancer and its impact on quality of life.Methods:The general information questionnaire,the Comprehensive Score for Financial Toxicity based on the Patient-Report Outcome Measures(COST-PROM),and the Functional Assessment of Cancer Therapy-Breast(FACT-B)were used to investigate 210 patients with breast cancer hospitalized in the department of breast oncology in a Class A tertiary hospital in Tianjin.Results:Patients with breast cancer scored 18.00(12.00,23.00)points in financial toxicity and(77.99±22.65)points in quality of life.65.7%of patients had financial toxicity.Spearman correlation analysis showed that the total score of financial toxicity was positively correlated with the total score of quality of life(r=0.567,P<0.01).Multiple linear regression analysis showed that chemotherapy and financial toxicity were the influencing factors of quality of life and explained 43.3%of the overall variation.Conclusion:The financial toxicity in patients with breast cancer is common.Chemotherapy and financial toxicity can significantly predict patients' quality of life.Nurses can implement targeted measures to reduce chemotherapy-related adverse reactions and reduce the level of financial toxicity,thereby improving patients'quality of life.