Since the COVID-19 outbreak,animal-mediated infectious diseases have been occurring around the world,and people need more species of experimental animals as research samples.Apodemus agrarius is a common farm rodent in China,with short breeding period and strong adaptability.It is widely distributed and is one of the main rodents affecting agricultural production in Chi-na.On the other hand,Apodemus agrarius is also a natural carrier of Hantavirus,Borrelia burgdorferi and Toxoplasma gondii,which is an important investigative sample in epidemiological studies,as well as being more advantageous in constructing disease models and probing the pathogenic mechanisms of pathogens,the research situation of its experimental animalization should be valued.The article summarized the classification and distribution,reproduction,physiology,molecular biology and the general situation of carrying pathogend.The reproduction studies,multi-omics applications,pathogen exploration and development prospects of the Apodemus a-grarius were discussed and outlooked,with a view to providing assistance for the subsequent development of experimental animal re-sources of the blackline guinea pig.
维普
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