首页|Peguero-Lo-Presti指数诊断的左心室肥厚与阵发性心房颤动射频导管消融术后复发的关系

Peguero-Lo-Presti指数诊断的左心室肥厚与阵发性心房颤动射频导管消融术后复发的关系

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目的 探讨Peguero-Lo-Presti指数诊断的左心室肥厚(LVH)与阵发性心房颤动(房颤)射频消融术后复发的关系.方法 选取成功接受射频导管消融的阵发性房颤患者652例.根据Peguero-Lo-Presti指数分为LVH组(167例)和左心室正常(LVN)组(485例).收集患者的基线资料,在射频导管消融术后3、6、12个月以及此后每12个月间隔进行规律随访,评估有无房颤复发;采用Kaplan-Meier法绘制2组的房颤复发曲线;Cox比例风险模型评估房颤复发的影响因素.结果 中位随访时间为20.5(15.0,26.0)个月,共155例(23.8%)患者出现复发,LVH组95例,LVN组60例,LVH组的无房颤复发率明显低于LVN组(64.1%vs.80.4%,Log-rank χ2=26.361,P<0.01).校正年龄、性别、体质量指数、高血压、糖尿病、冠心病、心功能不全、左房前后径、左室舒张末期内径和左室射血分数后,Peguero-Lo-Presti指数诊断的LVH仍是房颤复发的危险因素[HR(95%CI):2.359(1.663~3.345),P<0.01].结论 Peguero-Lo-Presti指数诊断的LVH是阵发性房颤患者射频导管消融术后复发的危险因素.
Relationship between left ventricular hypertrophy diagnosed by Peguero-Lo-Presti index and recurrence after radiofrequency catheter ablation of paroxysmal atrial fibrillation
Objective To investigate the relationship between left ventricular hypertrophy(LVH)diagnosed by Peguero-Lo-Presti index and recurrence of paroxysmal atrial fibrillation(AF)after radiofrequency ablation.Methods A total of 652 patients with paroxysmal atrial fibrillation who underwent radiofrequency ablation were selected.According to Peguero-Lo-Presti index,patients were divided into the LVH group(167 cases)and the normal left ventricle group(485 cases).Baseline data were collected,and regular follow-up was performed at 3,6 and 12 months after radiofrequency catheter ablation.The recurrence of AF was assessed.Kaplan-Meier survival curve was used to analyze the recurrence rate of AF in the two groups.Cox proportional hazard model was used to assess risk factors for recurrent atrial fibrillation.Results The median follow-up time was 20.5(15.0,26.0)months.A total of 155 patients(23.8%)developed recurrence of AF,including 95 patients in the LVH group and 60 patients in the LVN group.The recurrence rate without AF was significantly lower in the LVH group than that in the LVN group(64.1%vs.80.4%,Log-rank χ2=26.361,P<0.01).After adjusting for age,sex,body mass index,hypertension,diabetes,coronary heart disease,cardiac dysfunction,left anteroposterior and posterior atrial diameter,left ventricular end-diastolic diameter,and left ventricular ejection fraction,LVH diagnosed by Peguero-Lo-Presti index was still a risk factor for recurrent AF[HR(95%CI):2.359(1.663-3.345),P<0.01].Conclusion In patients with paroxysmal AF,LVH diagnosed by Peguero-Lo-Presti index is a risk factor of AF recurrence after radiofrequency catheter ablation.

hypertrophy,left ventricularatrial fibrillationradiofrequency ablationrecurrencePeguero-Lo-Presti index

张明龙、方媛媛、隋晓鹏、陈欣欣、李留东、王海涛

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中国人民解放军联勤保障部队第九七〇医院心内科(邮编 264010)

烟台毓璜顶医院心内科

肥大,左心室 心房颤动 射频消融术 复发 Peguero-Lo-Presti指数

2024

天津医药
天津市医学科学技术信息研究所

天津医药

CSTPCD
影响因子:1.107
ISSN:0253-9896
年,卷(期):2024.52(2)
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