首页|预防对比剂相关性急性肾损伤的研究进展

预防对比剂相关性急性肾损伤的研究进展

扫码查看
对比剂相关性急性肾损伤(CA-AKI)是在诊断或介入手术中使用对比剂所引起的一种严重并发症,目前已成为住院患者新发急性肾功能不全的主要原因之一.选择相对低毒的对比剂,减少对比剂暴露的时间和剂量对CA-AKI有一定的预防作用,他汀等药物以及术前术后的水化能够降低CA-AKI的风险,目前纳米药物已被证明在动物模型中获益.该文就当前CA-AKI的防治进行综述,为进一步深入研究新的干预措施奠定基础,并为临床治疗提供理论依据.
Research progress in the prevention of contrast-related acute kidney injury
Contrast-associated acute kidney injury(CA-AKI)is an important complication caused by the use of contrast medium(CM)in diagnostic or interventional surgery.At present,it has become one of the major causes of acute renal insufficiency in hospitalized patients.Choosing a relatively low toxic CM and reducing the exposure time and dose of CM can prevent CA-AKI occurrence to some extent.Drugs such as statins and postoperative hydration can reduce the risk of CA-AKI.In addition,nanomedicine has shown a benefit in animal models.This paper reviews the current prevention and treatment of CA-AKI to lay the foundation for further study of new interventions and provide a theoretical basis for clinical treatment.

contrast mediaacute kidney injuryhydroxymethylglutaryl-CoA reductase inhibitorsnanoparticlesfluid therapy

樊汇、马宇、李曦铭

展开 >

天津医科大学(邮编 300070)

天津大学胸科医院心血管内科

天津市心血管急危重症重点实验室

造影剂 急性肾损伤 羟甲基戊二酰基CoA还原酶抑制剂 纳米粒子 补液疗法

天津市卫生健康科技项目青年人才项目

TJWJ2021QN056

2024

天津医药
天津市医学科学技术信息研究所

天津医药

CSTPCD
影响因子:1.107
ISSN:0253-9896
年,卷(期):2024.52(3)
  • 26