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天津地区部分居民慢性阻塞性肺疾病影响因素分析

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目的 分析天津部分地区常住居民肺通气功能情况及拟诊慢性阻塞性肺疾病(COPD)的影响因素,为天津地区COPD的精准防控提供参考.方法 于2022年6月—12月随机抽取天津市和平区、津南区和宝坻区的35岁及以上的常住居民5 693例.收集基本信息、吸烟史、治疗用药,填写中国慢阻肺筛查问卷(COPD-SQ).根据COPD-SQ结果,将研究对象分为COPD低危组(COPD-SQ评分<16分,4 648例)及COPD高危组(COPD-SQ评分≥16分,1 045例).进行体格检查并完成肺功能筛查.采用多因素Logistic回归分析COPD患病的独立危险因素.结果 纳入对象年龄56(48,64)岁,男性2 393例(42.0%),吸烟1 381例(24.3%),体质量指数(BMI)25.1(23.0,27.6)kg/m2,腰臀比0.917(0.874,0.957),拟诊COPD 650例(11.4%);正在接受规范的COPD患者18例,占拟诊COPD人群的2.8%.与COPD低危组相比,COPD高危组男性占比、年龄、吸烟率、腰臀比、血压及拟诊COPD占比较高,BMI、外周经皮血氧饱和度、FVC占预计值的百分比、FEV1占预计值的百分比、1秒用力呼气量占用力肺活量百分比、呼气峰流量占预计值的百分比、最大呼气中期流量占预计值的百分比、PEF50占预计值的百分比较低(均P<0.05).和平区、津南区及宝坻区吸烟及拟诊COPD占比差异均有统计学意义(均P<0.05).多因素Logistic回归分析显示,男性、吸烟以及高龄是拟诊COPD的独立影响因素.结论 天津地区35岁及以上常住居民吸烟率较高,年龄、吸烟状况及性别均与COPD的发病相关.
Analysis of influencing factors of chronic obstructive pulmonary disease in permanent residents in some area of Tianjin
Objective To analyze the pulmonary ventilation function and influencing factors in residents in some area of Tianjin and provide a basis for the precise prevention and control of chronic obstructive pulmonary disease(COPD)in Tianjin.Methods A total of 5693 permanent residents aged 35 years and above in Heping District,Jinnan District and Baodi District of Tianjin were randomly selected from June to December 2022.The basic information,smoking history,treatment and China COPD Screening Questionnaire(COPD-SQ)were collected.According to the COPD-SQ result,the subjects were divided into the COPD low-risk group(COPD-SQ score<16 points,4 648 cases)and the COPD high-risk group(COPD-SQ score>16 points,1 045 cases).The physical examination and the pulmonary ventilation function testing were completed.Multivariate Logistic regression was used to analyze independent risk factors for COPD disease.Results The included subjects with the body quality index 25.1(23.0,27.6)kg/m2 were 56(48,64)years old,including 2 393(42.0%)men,1 381(24.3%)smokers and 650(11.4%)proposed COPD.Only 18 patients were received standard treatment,accounting for 2.8%of the patients with suspected COPD.Compared with the COPD low-risk group,the proportion of males and smokers,age,waist-to-hip ratio,blood pressure and proposed COPD were higher in the COPD high-risk group.BMI,peripheral percutaneous oxygen saturation,FVC percentage of predicted value,FEV1 percentage of predicted value,FEV1 percentage of FVC,PEF percentage of predicted value,MMEF percentage of predicted value,and PEF50 percentage of predicted value were lower(all P<0.05).The proportion of smokers and proposed COPD in Heping District,Jinnan District and Baodi District had statistical significance(P<0.05).The multivariate Logistic regression analysis showed that independent risk factors of COPD morbidity included gender,smoking and age(P<0.05).Conclusion The smoking rate of residents aged 35 and above in some area of Tianjin is high.Age,smoking status and gender are associated with the incidence of COPD.

pulmonary disease,chronic obstructivepulmonary ventilationrisk factorsepidemiologic studiesTianjin

冯李婷、李莉、谢鑫、王星

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天津大学海河医院呼吸与危重症医学科、天津市呼吸疾病研究所(邮编 300350)

肺疾病,慢性阻塞性 肺通气 危险因素 流行病学研究 天津

天津市医学重点学科专项建设项目天津市科技计划天津市卫生健康委-天津市中医药局-中医中西医结合科研课题

TJYXZDXK-063B22KPHDRC000902021148

2024

天津医药
天津市医学科学技术信息研究所

天津医药

CSTPCD
影响因子:1.107
ISSN:0253-9896
年,卷(期):2024.52(4)
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