Research progress on the role of Nrf2/HO-1 pathway in psoriasis
The pathogenesis of psoriasis is complex,so it is very important to explore the pathogenesis for the treatment of psoriasis.The Nrf2/HO-1 pathway has a protective effect on cells and is closely related to physiological and pathological aspects such as oxidative stress,immunity,abnormal proliferation of blood vessels,epidermal imbalance and cell death.Currently,some studies have confirmed that Nrf2/HO-1 pathway may have an inhibitory effect on psoriatic lesion,and it may be involved in psoriasis pathogenesis through multiple pathways.This paper reviews the mechanism of Nrf2/HO-1 pathway in psoriasis and the research progress in the treatment of psoriasis through the intervention of traditional Chinese medicine.
NF-E2-related factor 2heme oxygenase-1psoriasistraditional Chinese medicine and pharmacyoxidative stresscell death
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