The impact of preoperative anxiety on anesthesia and postoperative recovery in patients with liver cancer
Objective To investigate the effect of preoperative anxiety on postoperative recovery and short-term prognosis in patients with liver cancer resection.Methods A total of 96 patients underwent elective open hepatocellular carcinoma resection,with American Society of Anesthesiologists(ASA)grade Ⅰ-Ⅱ were included in this study.Patients were divided into the control group(41 cases,HAMA<7 points)and the anxiety group(55 cases,HAMA≥7 points)according to Hamilton Anxiety Scale(HAMA).Heart rate(HR),mean arterial pressure(MAP)after entering the operating room,operative time,intraoperative bleeding,intraoperative fluid infusion and intraoperative remifentanil consumption were monitored in patients.Recovery time,extubation time,Emergence Agitation(EA)score,the resting and dynamic visual analogue scale(VAS)at 5 min after extubation(T1),6 h(T2),12 h(T3),24h(T4)and 48 h(T5)after surgery,the cumulative effective pressing times of patient controlled analgesia(PCA),the remedy times of analgesic drugs,the postoperative gastrointestinal reaction,exhaust time,hospital stay,the serum alanine aminotransferase(ALT)and aspartate aminotransferase(AST)levels at the 5th day after operation were recorded.Results Compared with the control group,the heart rate and MAP in the anxious group were significantly increased after entering operating room,and the recovery time and extubation time were significantly prolonged(P＜0.05).The incidence of intraoperative remifentanil consumption,EA score,T1,T2,T3 resting and dynamic VAS score,T4 dynamic VAS score,PCA pressing times,analgesic drug remedy times and postoperative gastrointestinal reactions were significantly higher in the anxious group than those in the control group(P＜0.05),and incidence of gastrointestinal reactions,postoperative out of bed time,exhaust time,feeding time and hospital stay were significantly prolonged(P＜0.05).Conclusion Preoperative anxiety is not conducive to anesthesia recovery and short-term prognosis in patients with liver tumor resection.
carcinoma,hepatocellularanxietydelayed emergence from anesthesiapostoperative complications
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