首页|光学相干断层扫描血管成像技术在慢性肾脏病临床评估中的应用进展

光学相干断层扫描血管成像技术在慢性肾脏病临床评估中的应用进展

Application of optical coherence tomography angiography in clinical evaluation of chronic kidney disease

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慢性肾脏病(CKD)是常见的慢性疾病.视网膜和肾脏具有同源性.糖尿病视网膜病变、视网膜神经血管损伤均揭示了视网膜和肾脏存在共同的病理生理特征.光学相干断层扫描血管成像技术(OCTA)可用接近组织学的分辨率检测脉络膜视网膜微循环.由于微血管结构和功能的改变可促进高血压、糖尿病、CKD及相关心血管疾病(CVD)的发展.OCTA对CKD患者眼底神经微血管的检查有助于识别高危人群,评估CKD病情的进展,为CVD风险预测提供了新的视角;其与深度学习的结合,将会进一步拓展该方面研究.
Chronic kidney disease(CKD)is a common chronic disease.There is homology between retina and kidneys.Diabetic retinopathy and retinal neurovascular injury both reveal common pathophysiological features of ocular retina and kidney.Optical coherence tomography angiography(OCTA)detects chorioretinal microcirculation with near-histological resolution.Changes in microvascular structure and function can promote the development of hypertension,diabetes,CKD and related cardiovascular disease(CVD).The examination of fundus nerve microvessels by OCTA in patients with CKD is helpful to the identification of high-risk groups,and provides a new perspective for the assessment of disease progression and CVD risk prediction of patients with CKD.The combination of the deep learning will further expand this aspect of research and become the forefront of future development.

renal insufficiency,chronictomography,optical coherenceretinal vesselsdiabetic retinopathycardiovascular diseases

马良、胡立影、石羽、龙刚

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天津市人民医院肾脏病科(邮编 300121)

天津医科大学眼科医院临床研究中心

肾功能不全,慢性 体层摄影术,光学相干 视网膜血管 糖尿病视网膜病变 心血管疾病

天津市教委科研计划项目

2022KJ258

2024

天津医药
天津市医学科学技术信息研究所

天津医药

CSTPCD
影响因子:1.107
ISSN:0253-9896
年,卷(期):2024.52(8)