数字化技术在阿尔茨海默病中的应用进展
The application progress of digital technology in Alzheimer's disease
冉龙飞 1聂志强 1郭军辉2
作者信息
- 1. 北大医疗海洋石油医院康复医学中心(邮编 300452)
- 2. 北大医疗海洋石油医院康复医学中心(邮编 300452);北京大学工学院
- 折叠
摘要
阿尔茨海默病(AD)是一类以认知功能下降、精神行为异常、日常生活能力下降为临床表现的神经系统退行性疾病.该疾病病因多样,发病隐匿,传统神经心理学量表评估费时、影像学检测敏感度低、药物研发进展缓慢.随着认知神经科学和数字技术的迅速发展,AI、虚拟现实等数字化技术越来越受到关注.该文综述近年来数字化技术在AD的预测、筛查、辅助诊断和治疗领域的临床研究,以及数字化技术在AD步态、精细运动、语音等多领域的进展与突破,为临床诊疗和进一步探索提供方向.
Abstract
Alzheimer's disease(AD)is a neurodegenerative disease characterized by clinical manifestations of cognitive decline,abnormal mental behavior and decreased ability to engage in daily activities.The etiology of this disease is diverse and the onset is insidious.Traditional neuropsychological assessments are time-consuming,imaging detection sensitivity is low,and drug development progress is slow.With the rapid development of cognitive neuroscience and digital technology,digital technologies such as artificial intelligence and virtual reality are receiving increasing attention.This article aims to review the clinical research on digital technology in the prediction,screening,auxiliary diagnosis and treatment of AD in recent years,as well as the progress and breakthroughs in multiple fields such as AD gait,fine motor and speech,providing a directions for clinical diagnosis and further exploration.
关键词
阿尔茨海默病/AI/虚拟现实/数字化技术Key words
Alzheimer's disease/artificial intelligence/virtual reality/digital technology引用本文复制引用
基金项目
吴阶平医学基金会临床科研专项资助基金课题(320.6750.2023-15-12)
出版年
2024
NETL
NSTL
万方数据