Objective To explore the therapeutic effect of Shenqu Xiaoshi oral liquid combined with Xiyanping on children with rotavirus infected diarrhea and its impact on immune function.Methods A total of 200 children with rotavirus infected diarrhea were diveded into two groups according to treatment methods.The control group was treated with Xiyanping.The experimental group was treated with Shenqu Xiaoshi oral liquid combined with Xiyanping.The therapeutic effects and impacts on inflammatory factors and immune function were compared between the two groups.Results The total effective rate of clinical efficacy was higher in the experimental group than that in the control group(P＜0.05).After treatment,traditional Chinese medicine(TCM)syndrome scores,serum levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),interferon-γ(INF-γ),hypersensitive C-reactive protein(hs-CRP)and CD8+were lower in the experimental group than those in the control group(P＜0.05),the serum levels of CD3+,CD4+and CD4+/CD8+were higher than those of the control group(P＜0.05).The antidiarrheal time was earlier in the experimental group than that of the control group(P＜0.05),and the negative rate of stool rotavirus was higher than that of the control group(P＜0.05).Conclusion The combination of Shenqu Xiaoshi oral liquid and Xiyanping in the treatment of children with rotavirus infected diarrhea can quickly relieve symptoms of children,reduce inflammatory reactions and improve immune function.
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